Selected Publications

Type 2 IgG Memory B Cells and Long-Lived IgE Plasma Cells in the Persistence of Allergy

Miranda-Waldetario MCG, Fernandes-Braga W, Curotto de Lafaille MA. Immunol Rev. 2026 Jan;337(1):e70089. doi: 10.1111/imr.70089. PMID: 41508424.

Long-lived IgE plasma cells that reside in the spleen contribute to the persistence of the IgE response

Miranda-Waldetario MCG, Gonzalez-Kozlova E, Aguilar EC, Xie L, Hoehn KB, Aranda CJ, Garcia-Carmona Y, Ma EGM, Agudelo ES, Redes J, Curotto de Lafaille MA. Immunity. 2025 Nov 11;58(11):2717-2733.e7. doi: 10.1016/j.immuni.2025.10.011. Epub 2025 Oct 31. PMID: 41175873.

Advances in food allergy immunotherapy: Current strategies and role of antibody isotypes

Garcia-Carmona Y, Curotto de Lafaille MA. Cells. 2025, 14, 900. doi: 10.3390/cells14120900.

CD23+IgG1+ memory B cells are poised to switch to pathogenic IgE production in food allergy

Ota M, Hoehn KB, Fernandes-Braga W, Ota T, Aranda CJ, Friedman S, Miranda-Waldetario MGC, Redes J, Suprun M, Grishina G, Sampson HA, Malbari A, Kleinstein SH, Sicherer SH, Curotto de Lafaille MA. Sci Transl Med. 2024 Feb 7;16(733):eadi0673. doi: 10.1126/scitranslmed.adi0673. Epub 2024 Feb 7. PMID: 38324641; PMCID: PMC11008013.

Differential Tfh cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children

Lozano-Ojalvo, D, Chen X, Kazmi W, Menchén-Martínez D, Pérez-Rodríguez L, Fernandes-Braga W, Tyler S, Benkov K, Pittman N, Lai J, MD, Sampson HA, Curotto de Lafaille M, Dunkin D, and Berin, MC.  J. Allergy. Clin. Immunol. 2024 Oct 9:S0091-6749(24)01027-3. 

B cell memory of Immunoglobulin E (IgE) antibody responses in allergy

Fernandes-Braga W, Curotto de Lafaille MA.Curr Opin Immunol. 2024 Dec;91:102488. doi: 10.1016/j.coi.2024.102488. Epub 2024 Sep 27. PMID: 39340881.

Oral tolerance to dietary antigens and Foxp3+ regulatory T cells

Miranda-Waldetario MCG, Curotto de Lafaille MA. Immunol Rev. 2024;326:8-16. doi:10.1111/imr.13370.

IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases

Aranda CJ, Gonzalez-Kozlova E, Saunders SP, Fernandes-Braga W, Ota M, Narayanan S, He JS, Del Duca E, Swaroop B, Gnjatic S, Shattner G, Reibman J, Soter NA, Guttman-Yassky E, Curotto de Lafaille MA. Allergy. 2023 Mar;78(3):752-766. doi: 10.1111/all.15601. Epub 2022 Dec 19. PMID: 36445014; PMCID: PMC9991991.

Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans

Lozano-Ojalvo D, Tyler SR, Aranda CJ, Wang J, Sicherer S, Sampson HA, Wood RA, Burks AW, Jones SM, Leung DYM, Curotto de Lafaille M, Berin MC. Allergy. 2023 Mar;78(3):697-713.

Non-classical B Cell Memory of Allergic IgE Responses

Saunders SP, Ma EGM, Aranda CJ, Curotto de Lafaille MA. Front Immunol. 2019 Apr 26;10:715. doi: 10.3389/fimmu.2019.00715. PMID: 31105687; PMCID: PMC6498404.

IgG1 memory B cells keep the memory of IgE responses

Jin-Shu He, Sharrada Subramaniam, Vipin Narang, Kandhadayar Srinivasan, Sean P. Saunders, Daniel Carbajo, Tsao Wen-Shan, Nur Hidayah Hamadee, Josephine Lum, Andrea Lee, Jinmiao Chen, Michael Poidinger, Francesca Zolezzi, Juan J. Lafaille & Maria A. Curotto de Lafaille. Nature Communications. 8, 641 (2017). DOI: 10.1038/s41467-017-00723-0.

A subpopulation of high IL-21-producing CD4(+) T cells in Peyer's Patches is induced by the microbiota and regulates germinal centers

Jones L, Ho WQ, Ying S, Ramakrishna L, Srinivasan KG, Yurieva M, Ng WP, Subramaniam S, Hamadee NH, Joseph S, Dolpady J, Atarashi K, Honda K, Zolezzi F, Poidinger M, Lafaille JJ, Curotto de Lafaille MA. Sci Rep. 2016 Oct 10;6:34899. doi: 10.1038/srep34899. PMID: 27499025; PMCID: PMC4976330.

The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

He JS, Meyer-Hermann M, Xiangying D, Zuan LY, Jones LA, Ramakrishna L, de Vries VC, Dolpady J, Aina H, Joseph S, Narayanan S, Subramaniam S, Puthia M, Wong G, Xiong H, Poidinger M, Urban JF, Lafaille JJ, Curotto de Lafaille MA. J Exp Med. 2013 Nov 18;210(12):2755-71. doi: 10.1084/jem.20131539. Epub 2013 Nov 11. PMID: 24218137; PMCID: PMC3832920.

Sequential class switching is required for the generation of high-affinity IgE antibodies

Xiong H, Dolpady J, Wabl M, Curotto de Lafaille MA, Lafaille JJ. J Exp Med. 2012 Feb 13;209(2):353-64. doi: 10.1084/jem.20111941. Epub 2012 Jan 16. PMID: 22249450; PMCID: PMC3280879.

Adaptive Foxp3+ Regulatory T cell-dependent and -independent control of allergic inflammation

Curotto de Lafaille MA, Kutchukhidze N, Shen S, Ding Y, Yee H, and Lafaille JJ. Adaptive Foxp3+ Regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 29:114-126; 2008.  

Unique maturation program of the IgE response in vivo

Erazo A, Kutchukhidze N, Leung M, Christ AP, Urban JF Jr, Curotto de Lafaille MA, Lafaille JJ. Immunity. 2007 Feb;26(2):191-203. doi: 10.1016/j.immuni.2006.12.006. Epub 2007 Feb 8. PMID: 17292640; PMCID: PMC1892589.

Oral tolerance in the absence of naturally occurring regulatory T cells

Mucida D, Kutchukhidze N, Erazo A, Russo M, Lafaille JJ, and Curotto de Lafaille MA. J. Clin. Invest. 115:1923-33, 2005.